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High Glucose Induced Changes in Human VEC Phenotype in a 3D Hydrogel Derived From Cell-Free Native Aortic Root
Background: Valvular endothelial cells (VEC) have key roles in maintaining valvular integrity and homeostasis, and dysfunctional VEC are the initiators and major contributors to aortic valve disease in diabetes. Previous studies have shown that HG stimulated an inflammatory phenotype in VEC. Inflamm...
Autores principales: | Cecoltan, Sergiu, Ciortan, Letitia, Macarie, Razvan D., Vadana, Mihaela, Mihaila, Andreea C., Tucureanu, Monica, Vlad, Mihaela-Loredana, Droc, Ionel, Gherghiceanu, Mihaela, Simionescu, Agneta, Simionescu, Dan Teodor, Butoi, Elena, Manduteanu, Ileana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387830/ https://www.ncbi.nlm.nih.gov/pubmed/34458339 http://dx.doi.org/10.3389/fcvm.2021.714573 |
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