Pioglitazone mediates apoptosis in Caki cells via downregulating c-FLIP((L)) expression and reducing Bcl-2 protein stability

Pioglitazone is an anti-diabetic agent used in the treatment of type 2 diabetes, which belongs to the thiazolidinediones (TZDs) group. TZDs target peroxisome proliferator-activated receptor γ (PPARγ), which functions as a transcription factor of the nuclear hormone receptor. Pioglitazone has antitum...

Descripción completa

Detalles Bibliográficos
Autores principales: Jang, Ji Hoon, Lee, Tae-Jin, Sung, Eon-Gi, Song, In-Hwan, Kim, Joo-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387863/
https://www.ncbi.nlm.nih.gov/pubmed/34466155
http://dx.doi.org/10.3892/ol.2021.13004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387863/
https://www.ncbi.nlm.nih.gov/pubmed/34466155
http://dx.doi.org/10.3892/ol.2021.13004

Ejemplares similares