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Pioglitazone mediates apoptosis in Caki cells via downregulating c-FLIP((L)) expression and reducing Bcl-2 protein stability
Pioglitazone is an anti-diabetic agent used in the treatment of type 2 diabetes, which belongs to the thiazolidinediones (TZDs) group. TZDs target peroxisome proliferator-activated receptor γ (PPARγ), which functions as a transcription factor of the nuclear hormone receptor. Pioglitazone has antitum...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387863/ https://www.ncbi.nlm.nih.gov/pubmed/34466155 http://dx.doi.org/10.3892/ol.2021.13004 |