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Endoplasmic reticulum stress response and bile acid signatures associate with multi-strain seroresponsiveness during elderly influenza vaccination

The elderly are an important target for influenza vaccination, and the determination of factors that underlie immune responsiveness is clinically valuable. We evaluated the immune and metabolic profiles of 205 elderly Singaporeans administered with Vaxigrip. Despite high seroprotection rates, we obs...

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Detalles Bibliográficos
Autores principales: Carre, Christophe, Wong, Glenn, Narang, Vipin, Tan, Crystal, Chong, Joni, Chin, Hui Xian, Xu, Weili, Lu, Yanxia, Chua, Michelle, Poidinger, Michael, Tambyah, Paul, Nyunt, Ma, Ng, Tze Pin, Larocque, Daniel, Hessler, Catherine, Bosco, Nabil, Quemeneur, Laurence, Larbi, Anis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387917/
https://www.ncbi.nlm.nih.gov/pubmed/34471863
http://dx.doi.org/10.1016/j.isci.2021.102970