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Endoplasmic reticulum stress response and bile acid signatures associate with multi-strain seroresponsiveness during elderly influenza vaccination
The elderly are an important target for influenza vaccination, and the determination of factors that underlie immune responsiveness is clinically valuable. We evaluated the immune and metabolic profiles of 205 elderly Singaporeans administered with Vaxigrip. Despite high seroprotection rates, we obs...
Autores principales: | Carre, Christophe, Wong, Glenn, Narang, Vipin, Tan, Crystal, Chong, Joni, Chin, Hui Xian, Xu, Weili, Lu, Yanxia, Chua, Michelle, Poidinger, Michael, Tambyah, Paul, Nyunt, Ma, Ng, Tze Pin, Larocque, Daniel, Hessler, Catherine, Bosco, Nabil, Quemeneur, Laurence, Larbi, Anis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387917/ https://www.ncbi.nlm.nih.gov/pubmed/34471863 http://dx.doi.org/10.1016/j.isci.2021.102970 |
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