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Regulatory T cells enhance Th17 migration in psoriatic arthritis which is reversed by anti-TNF

Regulatory T cells (Treg) prevent the migration of effector T cells toward sites of inflammation, thereby limiting disease progression. We investigated this aspect of Treg function using psoriatic arthritis (PsA) as an exemplar of chronic inflammation. Patients with PsA had an increased Th17:Treg ra...

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Detalles Bibliográficos
Autores principales: Nguyen, Dao X., Baldwin, Helen M., Ezeonyeji, Amara N., Butt, Mohammed Rohan, Ehrenstein, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387926/
https://www.ncbi.nlm.nih.gov/pubmed/34471865
http://dx.doi.org/10.1016/j.isci.2021.102973