Cargando…
Regulatory T cells enhance Th17 migration in psoriatic arthritis which is reversed by anti-TNF
Regulatory T cells (Treg) prevent the migration of effector T cells toward sites of inflammation, thereby limiting disease progression. We investigated this aspect of Treg function using psoriatic arthritis (PsA) as an exemplar of chronic inflammation. Patients with PsA had an increased Th17:Treg ra...
Autores principales: | Nguyen, Dao X., Baldwin, Helen M., Ezeonyeji, Amara N., Butt, Mohammed Rohan, Ehrenstein, Michael R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387926/ https://www.ncbi.nlm.nih.gov/pubmed/34471865 http://dx.doi.org/10.1016/j.isci.2021.102973 |
Ejemplares similares
-
CD4 T-Cell Dysregulation in Psoriatic Arthritis Reveals a Regulatory Role for IL-22
por: Ezeonyeji, Amara, et al.
Publicado: (2017) -
Anti-TNF drives regulatory T cell expansion by paradoxically promoting membrane TNF–TNF-RII binding in rheumatoid arthritis
por: Nguyen, Dao Xuan, et al.
Publicado: (2016) -
Anti-TNF antibody therapy induces IL-17 suppressing regulatory T cells in patients with rheumatoid arthritis
por: McGovern, Jenny, et al.
Publicado: (2012) -
Compromised Function of Regulatory T Cells in Rheumatoid Arthritis and Reversal by Anti-TNFα Therapy
por: Ehrenstein, Michael R., et al.
Publicado: (2004) -
Th17 and Th22 cells in psoriatic arthritis and psoriasis
por: Benham, Helen, et al.
Publicado: (2013)