Regulation of NADPH Oxidase-Mediated Superoxide Production by Acetylation and Deacetylation

Oral treatment of apolipoprotein E-knockout (ApoE-KO) mice with the putative sirtuin 1 (SIRT1) activator resveratrol led to a reduction of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity in the heart. In contrast, the SIRT1 inhibitor EX527 enhanced the superoxide production in i...

Descripción completa

Detalles Bibliográficos
Autores principales: Xia, Ning, Tenzer, Stefan, Lunov, Oleg, Karl, Martin, Simmet, Thomas, Daiber, Andreas, Münzel, Thomas, Reifenberg, Gisela, Förstermann, Ulrich, Li, Huige
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387964/
https://www.ncbi.nlm.nih.gov/pubmed/34456745
http://dx.doi.org/10.3389/fphys.2021.693702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387964/
https://www.ncbi.nlm.nih.gov/pubmed/34456745
http://dx.doi.org/10.3389/fphys.2021.693702

Ejemplares similares