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Regulation of NADPH Oxidase-Mediated Superoxide Production by Acetylation and Deacetylation

Oral treatment of apolipoprotein E-knockout (ApoE-KO) mice with the putative sirtuin 1 (SIRT1) activator resveratrol led to a reduction of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity in the heart. In contrast, the SIRT1 inhibitor EX527 enhanced the superoxide production in i...

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Detalles Bibliográficos
Autores principales:	Xia, Ning, Tenzer, Stefan, Lunov, Oleg, Karl, Martin, Simmet, Thomas, Daiber, Andreas, Münzel, Thomas, Reifenberg, Gisela, Förstermann, Ulrich, Li, Huige
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387964/ https://www.ncbi.nlm.nih.gov/pubmed/34456745 http://dx.doi.org/10.3389/fphys.2021.693702

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