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Inferring perturbation profiles of cancer samples

MOTIVATION: Cancer is one of the most prevalent diseases in the world. Tumors arise due to important genes changing their activity, e.g. when inhibited or over-expressed. But these gene perturbations are difficult to observe directly. Molecular profiles of tumors can provide indirect evidence of gen...

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Detalles Bibliográficos
Autores principales: Pirkl, Martin, Beerenwinkel, Niko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8388028/
https://www.ncbi.nlm.nih.gov/pubmed/33617647
http://dx.doi.org/10.1093/bioinformatics/btab113