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K(Ca)3.1 Inhibition Decreases Size and Alters Composition of Atherosclerotic Lesions Induced by Low, Oscillatory Flow

Low, oscillatory flow/shear patterns are associated with atherosclerotic lesion development. Increased expression of K(Ca)3.1 has been found in Vascular Smooth Muscle (VSM), macrophages and T-cells in lesions from humans and mice. Increased expression of K(Ca)3.1, is also required for VSM cell proli...

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Detalles Bibliográficos
Autores principales: Tharp, Darla L., Bowles, Douglas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8388312/
https://www.ncbi.nlm.nih.gov/pubmed/34457083
http://dx.doi.org/10.2991/artres.k.210202.001