Cargando…
K(Ca)3.1 Inhibition Decreases Size and Alters Composition of Atherosclerotic Lesions Induced by Low, Oscillatory Flow
Low, oscillatory flow/shear patterns are associated with atherosclerotic lesion development. Increased expression of K(Ca)3.1 has been found in Vascular Smooth Muscle (VSM), macrophages and T-cells in lesions from humans and mice. Increased expression of K(Ca)3.1, is also required for VSM cell proli...
Autores principales: | Tharp, Darla L., Bowles, Douglas K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8388312/ https://www.ncbi.nlm.nih.gov/pubmed/34457083 http://dx.doi.org/10.2991/artres.k.210202.001 |
Ejemplares similares
-
Upregulation of Intermediate-Conductance Ca(2+)-Activated K(+) Channels (KCNN4) in Porcine Coronary Smooth Muscle Requires NADPH Oxidase 5 (NOX5)
por: Gole, Hope K. A., et al.
Publicado: (2014) -
Myeloperoxidase inhibition in mice alters atherosclerotic lesion composition
por: Roth Flach, Rachel J., et al.
Publicado: (2019) -
Endurance exercise training does not limit coronary atherosclerosis in familial hypercholesterolemic swine
por: Tharp, Darla L., et al.
Publicado: (2019) -
TWEAK blockade decreases atherosclerotic lesion size and progression through suppression of STAT1 signaling in diabetic mice
por: Fernández-Laso, Valvanera, et al.
Publicado: (2017) -
Modulation of Cardiovascular Function in Primary Hypertension in Rat by SKA-31, an Activator of K(Ca)2.x and K(Ca)3.1 Channels
por: Kloza, Monika, et al.
Publicado: (2019)