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Construction of an Artificial Biosynthetic Pathway for the Styrylpyrone Compound 11-Methoxy-Bisnoryangonin Produced in Engineered Escherichia coli

A cDNA clone (named pnpks), which shows high homology to the known chalcone synthase (CHS)-like type III PKS, was obtained from the leaves of Piper nigrum. The PnPKS protein with ferulic acid catalyzed lactonization instead of chalcone or stilbene formation. The new product was characterized as a st...

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Detalles Bibliográficos
Autores principales: Heo, Kyung Taek, Lee, Byeongsan, Jang, Jae-Hyuk, Ahn, Jung-Oh, Hong, Young-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8388576/
https://www.ncbi.nlm.nih.gov/pubmed/34456894
http://dx.doi.org/10.3389/fmicb.2021.714335