Cinnamaldehyde elicits itch behavior via TRPV1 and TRPV4 but not TRPA1

INTRODUCTION: Cinnamaldehyde (CA) elicits itch sensation in humans. We investigated if CA elicits scratching behavior in mice and determined the roles for TRPV1, TRPA1, and TRPV4. MATERIALS AND METHODS: Scratching behavior elicited by intradermal injection of CA was assessed in wildtype (WT) mice an...

Descripción completa

Detalles Bibliográficos
Autores principales: Domocos, Dan, Follansbee, Taylor, Nguyen, Amanda, Nguyen, Tony, Carstens, Mirela I., Carstens, Earl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8388579/
https://www.ncbi.nlm.nih.gov/pubmed/34458578
http://dx.doi.org/10.1097/itx.0000000000000036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8388579/
https://www.ncbi.nlm.nih.gov/pubmed/34458578
http://dx.doi.org/10.1097/itx.0000000000000036

Ejemplares similares