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Cinnamaldehyde elicits itch behavior via TRPV1 and TRPV4 but not TRPA1

INTRODUCTION: Cinnamaldehyde (CA) elicits itch sensation in humans. We investigated if CA elicits scratching behavior in mice and determined the roles for TRPV1, TRPA1, and TRPV4. MATERIALS AND METHODS: Scratching behavior elicited by intradermal injection of CA was assessed in wildtype (WT) mice an...

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Detalles Bibliográficos
Autores principales:	Domocos, Dan, Follansbee, Taylor, Nguyen, Amanda, Nguyen, Tony, Carstens, Mirela I., Carstens, Earl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8388579/ https://www.ncbi.nlm.nih.gov/pubmed/34458578 http://dx.doi.org/10.1097/itx.0000000000000036

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