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Diabetic Embryopathy Susceptibility in Mice Is Associated with Differential Dependence on Glucosamine and Modulation of High Glucose-Induced Oxidative Stress

The high K(M) glucose transporter, GLUT2 (SLC2A2), is expressed by embryos and causes high rates of glucose transport during maternal hyperglycemic episodes in diabetic pregnancies and causes congenital malformations (diabetic embryopathy). GLUT2 is also a low K(M) transporter of the amino sugar, gl...

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Detalles Bibliográficos
Autores principales: Jung, Jin Hyuk, Loeken, Mary R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8388881/
https://www.ncbi.nlm.nih.gov/pubmed/34439404
http://dx.doi.org/10.3390/antiox10081156