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The Revival of Aztreonam in Combination with Avibactam against Metallo-β-Lactamase-Producing Gram-Negatives: A Systematic Review of In Vitro Studies and Clinical Cases

Infections caused by metallo-β-lactamase (MBL)-producing Enterobacterales and Pseudomonas are increasingly reported worldwide and are usually associated with high mortality rates (>30%). Neither standard therapy nor consensus for the management of these infections exist. Aztreonam, an old β-lacta...

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Detalles Bibliográficos
Autores principales: Mauri, Carola, Maraolo, Alberto Enrico, Di Bella, Stefano, Luzzaro, Francesco, Principe, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8388901/
https://www.ncbi.nlm.nih.gov/pubmed/34439062
http://dx.doi.org/10.3390/antibiotics10081012