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Supplemental Ferulic Acid Inhibits Total Body Irradiation-Mediated Bone Marrow Damage, Bone Mass Loss, Stem Cell Senescence, and Hematopoietic Defect in Mice by Enhancing Antioxidant Defense Systems

While total body irradiation (TBI) is an everlasting curative therapy, the irradiation can cause long-term bone marrow (BM) injuries, along with senescence of hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs) via reactive oxygen species (ROS)-induced oxidative damages. Thus, ameliora...

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Detalles Bibliográficos
Autores principales: Wagle, Sajeev, Sim, Hyun-Jaung, Bhattarai, Govinda, Choi, Ki-Choon, Kook, Sung-Ho, Lee, Jeong-Chae, Jeon, Young-Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8388974/
https://www.ncbi.nlm.nih.gov/pubmed/34439457
http://dx.doi.org/10.3390/antiox10081209