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Design, Synthesis and Antifungal Activity of Stapled Aurein1.2 Peptides

Aurein1.2 is a 13-residue antimicrobial peptide secreted by the Australian tree frog Litoria aurea. In order to improve its stabilities, the helical contents and corresponding biological activities of Aurein1.2 (a series of stapled analogues) were synthesized, and their potential antifungal activiti...

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Detalles Bibliográficos
Autores principales: Zheng, Mengjun, Wang, Ruina, Chen, Si, Zou, Yan, Yan, Lan, Zhao, Linjing, Li, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389037/
https://www.ncbi.nlm.nih.gov/pubmed/34439006
http://dx.doi.org/10.3390/antibiotics10080956