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Opioid Withdrawal Produces Sex-Specific Effects on Fentanyl-Versus-Food Choice and Mesolimbic Transcription

BACKGROUND: Opioid withdrawal is a key driver of opioid addiction and an obstacle to recovery. However, withdrawal effects on opioid reinforcement and mesolimbic neuroadaptation are understudied, and the role of sex is largely unknown. METHODS: Male (n = 13) and female (n = 12) rats responded under...

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Detalles Bibliográficos
Autores principales: Townsend, E. Andrew, Kim, R. Kijoon, Robinson, Hannah L., Marsh, Samuel A., Banks, Matthew L., Hamilton, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389189/
https://www.ncbi.nlm.nih.gov/pubmed/34458885
http://dx.doi.org/10.1016/j.bpsgos.2021.04.009