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Opioid Withdrawal Produces Sex-Specific Effects on Fentanyl-Versus-Food Choice and Mesolimbic Transcription
BACKGROUND: Opioid withdrawal is a key driver of opioid addiction and an obstacle to recovery. However, withdrawal effects on opioid reinforcement and mesolimbic neuroadaptation are understudied, and the role of sex is largely unknown. METHODS: Male (n = 13) and female (n = 12) rats responded under...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389189/ https://www.ncbi.nlm.nih.gov/pubmed/34458885 http://dx.doi.org/10.1016/j.bpsgos.2021.04.009 |