New Approach for Detection of Normal Alternative Splicing Events and Aberrant Spliceogenic Transcripts with Long-Range PCR and Deep RNA Sequencing

SIMPLE SUMMARY: RNA splicing defects, caused by genetic variants, are a common molecular mechanism of disease. To detect variants that cause splicing impairment, mRNA-based studies must be performed. Classical mRNA assays are time-consuming, which is why we have validated a new reliable straightforw...

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Detalles Bibliográficos
Autores principales: Dragoš, Vita Šetrajčič, Stegel, Vida, Blatnik, Ana, Klančar, Gašper, Krajc, Mateja, Novaković, Srdjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389194/
https://www.ncbi.nlm.nih.gov/pubmed/34439939
http://dx.doi.org/10.3390/biology10080706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389194/
https://www.ncbi.nlm.nih.gov/pubmed/34439939
http://dx.doi.org/10.3390/biology10080706

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