Malaria Pigment Hemozoin Impairs GM-CSF Receptor Expression and Function by 4-Hydroxynonenal

Malarial pigment hemozoin (HZ) generates the lipoperoxidation product 4-hydroxynonenal (4-HNE), which is known to cause dysregulation of the immune response in malaria. The inhibition of granulocyte macrophage colony-stimulating factor (GM-CSF)-dependent differentiation of dendritic cells (DC) by HZ...

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Detalles Bibliográficos
Autores principales: Skorokhod, Oleksii, Barrera, Valentina, Mandili, Giorgia, Costanza, Federica, Valente, Elena, Ulliers, Daniela, Schwarzer, Evelin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389202/
https://www.ncbi.nlm.nih.gov/pubmed/34439507
http://dx.doi.org/10.3390/antiox10081259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389202/
https://www.ncbi.nlm.nih.gov/pubmed/34439507
http://dx.doi.org/10.3390/antiox10081259

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