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The Impact of Melatonin Supplementation and NLRP3 Inflammasome Deletion on Age-Accompanied Cardiac Damage

To investigate the role of NLRP3 inflammasome in cardiac aging, we evaluate here morphological and ultrastructural age-related changes of cardiac muscles fibers in wild-type and NLRP3-knockout mice, as well as studying the beneficial effect of melatonin therapy. The results clarified the beginning o...

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Detalles Bibliográficos
Autores principales: Sayed, Ramy K. A., Fernández-Ortiz, Marisol, Rahim, Ibtissem, Fernández-Martínez, José, Aranda-Martínez, Paula, Rusanova, Iryna, Martínez-Ruiz, Laura, Alsaadawy, Reem M., Escames, Germaine, Acuña-Castroviejo, Darío
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389221/
https://www.ncbi.nlm.nih.gov/pubmed/34439517
http://dx.doi.org/10.3390/antiox10081269