MicroRNA-29a Mitigates Osteoblast Senescence and Counteracts Bone Loss through Oxidation Resistance-1 Control of FoxO3 Methylation

Senescent osteoblast overburden accelerates bone mass loss. Little is understood about microRNA control of oxidative stress and osteoblast senescence in osteoporosis. We revealed an association between microRNA-29a (miR-29a) loss, oxidative stress marker 8-hydroxydeoxyguanosine (8-OHdG), DNA hyperme...

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Detalles Bibliográficos
Autores principales: Lian, Wei-Shiung, Wu, Re-Wen, Chen, Yu-Shan, Ko, Jih-Yang, Wang, Shao-Yu, Jahr, Holger, Wang, Feng-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389244/
https://www.ncbi.nlm.nih.gov/pubmed/34439496
http://dx.doi.org/10.3390/antiox10081248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389244/
https://www.ncbi.nlm.nih.gov/pubmed/34439496
http://dx.doi.org/10.3390/antiox10081248

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