The Alteration of Chloride Homeostasis/GABAergic Signaling in Brain Disorders: Could Oxidative Stress Play a Role?

In neuronal precursors and immature neurons, the depolarizing (excitatory) effect of γ-Aminobutyric acid (GABA) signaling is associated with elevated [Cl(−)](i); as brain cells mature, a developmental switch occurs, leading to the decrease of [Cl(−)](i) and to the hyperpolarizing (inhibitory) effect...

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Detalles Bibliográficos
Autores principales: Abruzzo, Provvidenza M., Panisi, Cristina, Marini, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389245/
https://www.ncbi.nlm.nih.gov/pubmed/34439564
http://dx.doi.org/10.3390/antiox10081316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389245/
https://www.ncbi.nlm.nih.gov/pubmed/34439564
http://dx.doi.org/10.3390/antiox10081316

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