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Entamoeba histolytica Adaption to Auranofin: A Phenotypic and Multi-Omics Characterization

Auranofin (AF), an antirheumatic agent, targets mammalian thioredoxin reductase (TrxR), an important enzyme controlling redox homeostasis. AF is also highly effective against a diversity of pathogenic bacteria and protozoan parasites. Here, we report on the resistance of the parasite Entamoeba histo...

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Detalles Bibliográficos
Autores principales: Shaulov, Yana, Sarid, Lotem, Trebicz-Geffen, Meirav, Ankri, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389260/
https://www.ncbi.nlm.nih.gov/pubmed/34439488
http://dx.doi.org/10.3390/antiox10081240