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Entamoeba histolytica Adaption to Auranofin: A Phenotypic and Multi-Omics Characterization
Auranofin (AF), an antirheumatic agent, targets mammalian thioredoxin reductase (TrxR), an important enzyme controlling redox homeostasis. AF is also highly effective against a diversity of pathogenic bacteria and protozoan parasites. Here, we report on the resistance of the parasite Entamoeba histo...
Autores principales: | Shaulov, Yana, Sarid, Lotem, Trebicz-Geffen, Meirav, Ankri, Serge |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389260/ https://www.ncbi.nlm.nih.gov/pubmed/34439488 http://dx.doi.org/10.3390/antiox10081240 |
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