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Isoorientin Attenuated the Pyroptotic Hepatocyte Damage Induced by Benzo[a]pyrene via ROS/NF-κB/NLRP3/Caspase-1 Signaling Pathway

Isoorientin (Iso), a natural bioactive flavonoid, possesses significant anti-tumor and anti-oxidant activities. Benzo[a]pyrene (BaP) is a food processing injurant with carcinogenicity, teratogenicity, and genotoxicity. Our preliminary study demonstrates that Iso attenuated the pyroptotic hepatocyte...

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Detalles Bibliográficos
Autores principales: Li, Hao, Yuan, Li, Li, Xueyi, Luo, Ying, Zhang, Zhong, Li, Jianke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389279/
https://www.ncbi.nlm.nih.gov/pubmed/34439523
http://dx.doi.org/10.3390/antiox10081275