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Targeting Pro-Oxidant Iron with Deferoxamine as a Treatment for Ischemic Stroke: Safety and Optimal Dose Selection in a Randomized Clinical Trial

A role of iron as a target to prevent stroke-induced neurodegeneration has been recently revisited due to new evidence showing that ferroptosis inhibitors are protective in experimental ischemic stroke and might be therapeutic in other neurodegenerative brain pathologies. Ferroptosis is a new form o...

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Detalles Bibliográficos
Autores principales: Millán, Mònica, DeGregorio-Rocasolano, Núria, Pérez de la Ossa, Natàlia, Reverté, Sílvia, Costa, Joan, Giner, Pilar, Silva, Yolanda, Sobrino, Tomás, Rodríguez-Yáñez, Manuel, Nombela, Florentino, Campos, Francisco, Serena, Joaquín, Vivancos, José, Martí-Sistac, Octavi, Cortés, Jordi, Dávalos, Antoni, Gasull, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389327/
https://www.ncbi.nlm.nih.gov/pubmed/34439518
http://dx.doi.org/10.3390/antiox10081270