Cargando…
TRPM2 Non-Selective Cation Channels in Liver Injury Mediated by Reactive Oxygen Species
TRPM2 channels admit Ca(2+) and Na(+) across the plasma membrane and release Ca(2+) and Zn(2+) from lysosomes. Channel activation is initiated by reactive oxygen species (ROS), leading to a subsequent increase in ADP-ribose and the binding of ADP-ribose to an allosteric site in the cytosolic NUDT9 h...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389341/ https://www.ncbi.nlm.nih.gov/pubmed/34439491 http://dx.doi.org/10.3390/antiox10081243 |