Inhibition of immunoproteasome subunit low molecular mass polypeptide 7 with ONX-0914 improves hypoxic-ischemic brain damage via PI3K/Akt signaling

The immunoproteasome subunit low molecular mass polypeptide 7 (LMP7) leads to brain injuries, such as autoimmune neuritis and ischemic stroke, by activating inflammation. However, the roles and mechanisms of LMP7 in hypoxic-ischemic brain damage (HIBD) remain unclear. This study explored these issue...

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Detalles Bibliográficos
Autores principales: Zhou, Yue, Gou, Zhixian, Huang, Lin, Fan, Yang, Zhang, Feng, Lu, Liqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Cellular, Molecular and Developmental Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389355/
https://www.ncbi.nlm.nih.gov/pubmed/34406990
http://dx.doi.org/10.1097/WNR.0000000000001715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389355/
https://www.ncbi.nlm.nih.gov/pubmed/34406990
http://dx.doi.org/10.1097/WNR.0000000000001715

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