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Role of Ras in regulation of intestinal epithelial cell homeostasis and crosstalk with Wnt signaling

Cross talk between different signaling pathways is thought to be important for regulation of homeostasis of, as well as oncogenesis of, the intestinal epithelium. Expression of an active form of K-Ras specifically in intestinal epithelial cells (IECs) of mice (IEC-RasDA mice) resulted in the develop...

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Detalles Bibliográficos
Autores principales: Kotani, Takenori, Ihara, Noriko, Okamoto, Saki, Setiawan, Jajar, Konno, Tasuku, Saito, Yasuyuki, Murata, Yoji, Matozaki, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389409/
https://www.ncbi.nlm.nih.gov/pubmed/34437645
http://dx.doi.org/10.1371/journal.pone.0256774