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CRIF1 deficiency suppresses endothelial cell migration via upregulation of RhoGDI2

Rho GDP-dissociation inhibitor (RhoGDI), a downregulator of Rho family GTPases, prevents nucleotide exchange and membrane association. It is responsible for the activation of Rho GTPases, which regulate a variety of cellular processes, such as migration. Although RhoGDI2 has been identified as a tum...

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Detalles Bibliográficos
Autores principales: Nagar, Harsha, Kim, Seonhee, Lee, Ikjun, Choi, Su-Jeong, Piao, Shuyu, Jeon, Byeong Hwa, Shong, Minho, Kim, Cuk-Seong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389428/
https://www.ncbi.nlm.nih.gov/pubmed/34437633
http://dx.doi.org/10.1371/journal.pone.0256646