Effect of TGF-β1 on eosinophils to induce cysteinyl leukotriene E(4) production in aspirin-exacerbated respiratory disease

Cysteinyl leukotriene (cysLT) overproduction and eosinophil activation are hallmarks of aspirin-exacerbated respiratory disease (AERD). However, pathogenic mechanisms of AERD remain to be clarified. Here, we aimed to find the significance of transforming growth factor beta 1 (TGF-β1) in association...

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Detalles Bibliográficos
Autores principales: Choi, Youngwoo, Sim, Soyoon, Lee, Dong-Hyun, Lee, Hee-Ra, Ban, Ga-Young, Shin, Yoo Seob, Kim, Yoon-Keun, Park, Hae-Sim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389430/
https://www.ncbi.nlm.nih.gov/pubmed/34437574
http://dx.doi.org/10.1371/journal.pone.0256237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389430/
https://www.ncbi.nlm.nih.gov/pubmed/34437574
http://dx.doi.org/10.1371/journal.pone.0256237

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