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miR-519d downregulates LEP expression to inhibit preeclampsia development

The purpose of the current study was to characterize role of microRNA (miR)-519d in trophoblast cells and preeclampsia (PE) development and its potential underlying mechanism. Regulation of leptin (LEP) by miR-519d was verified using a dual-luciferase reporter gene assay. Loss- and gain-of-function...

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Detalles Bibliográficos
Autores principales: Cai, Hairui, Li, Dongmei, Wu, Jun, Shi, Chunbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389502/
https://www.ncbi.nlm.nih.gov/pubmed/34514168
http://dx.doi.org/10.1515/med-2021-0244