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All-Atom Simulations Reveal a Key Interaction Network in the HLA-E/NKG2A/CD94 Immune Complex Fine-Tuned by the Nonameric Peptide

[Image: see text] Natural killer (NK) cells, an important part of the innate immune system, can clear a wide variety of pathological challenges, including tumor, senescent, and virally infected cells. They express various activating and inhibitory receptors on their surface, and the balance of inter...

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Detalles Bibliográficos
Autores principales: Prašnikar, Eva, Perdih, Andrej, Borišek, Jure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389527/
https://www.ncbi.nlm.nih.gov/pubmed/34196180
http://dx.doi.org/10.1021/acs.jcim.1c00414