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Reconstruction of the Fas-Based Death-Inducing Signaling Complex (DISC) Using a Protein–Protein Docking Meta-Approach

[Image: see text] The death-inducing signaling complex (DISC) is a fundamental multiprotein complex, which triggers the extrinsic apoptosis pathway through stimulation by death ligands. DISC consists of different death domain (DD) and death effector domain (DED) containing proteins such as the death...

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Detalles Bibliográficos
Autores principales: Mahdizadeh, Sayyed Jalil, Thomas, Melissa, Eriksson, Leif A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389534/
https://www.ncbi.nlm.nih.gov/pubmed/34196179
http://dx.doi.org/10.1021/acs.jcim.1c00301