CD40 Agonist Monoclonal Antibody-Mediated Hepatitis in TNF-Receptor 1 Gene Knockout Mice

Tumor necrosis factor-alpha (TNF-α) plays an important role in liver inflammation. CD40-CD40 ligand (CD40-CD40L) is a key receptor–ligand signaling pair involved in the adaptive immune response and pathogenesis of autoimmune diseases. In mice, CD40 activation leads to sickness behavior syndrome (SBS...

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Detalles Bibliográficos
Autores principales: Raabe, Oksana, Birchler, Thomas, Rehrauer, Hubert, Eppler, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389574/
https://www.ncbi.nlm.nih.gov/pubmed/34440067
http://dx.doi.org/10.3390/biomedicines9080863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389574/
https://www.ncbi.nlm.nih.gov/pubmed/34440067
http://dx.doi.org/10.3390/biomedicines9080863

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