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Acute blockade of endogenous melatonin by Luzindole, with or without peripheral LPS injection, induces jejunal inflammation and morphological alterations in Swiss mice

This study investigated the acute blockade of endogenous melatonin (MLT) using Luzindole with or without systemic lipopolysaccharide (LPS) challenge and evaluated changes in inflammatory and oxidative stress markers in the mouse jejunum. Luzindole is an MT1/MT2 MLT receptor antagonist. Both receptor...

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Detalles Bibliográficos
Autores principales: Matos, R.S., Oriá, R.B., Bruin, P.F.C., Pinto, D.V., Viana, A.F.S.C., Santos, F.A., Duarte, A.S.G., Bruin, V.M.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389610/
https://www.ncbi.nlm.nih.gov/pubmed/34431873
http://dx.doi.org/10.1590/1414-431X2021e11215