Bcl-xL Is Required by Primary Hippocampal Neurons during Development to Support Local Energy Metabolism at Neurites

SIMPLE SUMMARY: B-cell lymphoma-extra large (Bcl-xL) is an anti-apoptotic protein that regulates energy metabolism in neurons. In this study, we found that primary hippocampal neurons transduced with Bcl-xL shRNA or treated with a pharmacological inhibitor of Bxl-xL had a decrease in the population...

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Detalles Bibliográficos
Autores principales: Jansen, Joseph, Scott, Madison, Amjad, Emma, Stumpf, Allison, Lackey, Kimberly H., Caldwell, Kim A., Park, Han-A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389656/
https://www.ncbi.nlm.nih.gov/pubmed/34440004
http://dx.doi.org/10.3390/biology10080772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389656/
https://www.ncbi.nlm.nih.gov/pubmed/34440004
http://dx.doi.org/10.3390/biology10080772

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