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Proteolyzed Variant of IgG with Free C-Terminal Lysine as a Biomarker of Prostate Cancer

SIMPLE SUMMARY: We have discovered that immunoglobulins digested with plasmin, one of the enzymes of blood clotting cascade acquire a capability to bind to one of the chains of plasminogen. We investigate here the mechanisms and localization of such binding. We also show that levels of this digested...

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Detalles Bibliográficos
Autores principales: Lokshin, Anna, Mikhaleva, Lyudmila M., Goufman, Eugene I., Boltovskaya, Marina N., Tikhonova, Natalia B., Stepanova, Irina I., Stepanov, Alexandr A., Potoldykova, Natalia V., Vinarov, Andrey Z., Stemmer, Paul, Iakovlev, Vasily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389667/
https://www.ncbi.nlm.nih.gov/pubmed/34440049
http://dx.doi.org/10.3390/biology10080817