Purification and In Vitro Evaluation of an Anti-HER2 Affibody-Monomethyl Auristatin E Conjugate in HER2-Positive Cancer Cells

SIMPLE SUMMARY: Antibody-drug conjugates (ADCs) represent an innovative class of anticancer agents specifically aimed at targeting cancer cells, reducing damage to healthy tissues but showing some weaknesses. A promising approach for the development of high-affinity tumor targeting ADCs is the use o...

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Detalles Bibliográficos
Autores principales: Damiani, Isabella, Castiglioni, Silvia, Sochaj-Gregorczyk, Alicja, Bonacina, Fabrizia, Colombo, Irma, Rusconi, Valentina, Otlewski, Jacek, Corsini, Alberto, Bellosta, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389717/
https://www.ncbi.nlm.nih.gov/pubmed/34439990
http://dx.doi.org/10.3390/biology10080758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389717/
https://www.ncbi.nlm.nih.gov/pubmed/34439990
http://dx.doi.org/10.3390/biology10080758

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