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Purification and In Vitro Evaluation of an Anti-HER2 Affibody-Monomethyl Auristatin E Conjugate in HER2-Positive Cancer Cells
SIMPLE SUMMARY: Antibody-drug conjugates (ADCs) represent an innovative class of anticancer agents specifically aimed at targeting cancer cells, reducing damage to healthy tissues but showing some weaknesses. A promising approach for the development of high-affinity tumor targeting ADCs is the use o...
Autores principales: | Damiani, Isabella, Castiglioni, Silvia, Sochaj-Gregorczyk, Alicja, Bonacina, Fabrizia, Colombo, Irma, Rusconi, Valentina, Otlewski, Jacek, Corsini, Alberto, Bellosta, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389717/ https://www.ncbi.nlm.nih.gov/pubmed/34439990 http://dx.doi.org/10.3390/biology10080758 |
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