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Emerging Therapeutic Potential of SIRT6 Modulators

[Image: see text] Sirtuin 6 (SIRT6) is an NAD(+)-dependent protein deacylase and mono-ADP-ribosyltransferase of the sirtuin family with a wide substrate specificity. In vitro and in vivo studies have indicated that SIRT6 overexpression or activation has beneficial effects for cellular processes such...

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Detalles Bibliográficos
Autores principales: Fiorentino, Francesco, Mai, Antonello, Rotili, Dante
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389836/
https://www.ncbi.nlm.nih.gov/pubmed/34213345
http://dx.doi.org/10.1021/acs.jmedchem.1c00601