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The Future of Medicinal Chemistry, PROTAC, and Undruggable Drug Targets
WRD5 is a promising target for anticancer drug discovery. In addition, it plays a vital role in epigenetic regulation. Since biological inactivation of WRD5 is difficult to reach via classical approach, PROTACs (Proteolysis Targeting Chimeras) are offering a new option. In a study, published in this...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389887/ https://www.ncbi.nlm.nih.gov/pubmed/34296872 http://dx.doi.org/10.1021/acs.jmedchem.1c01126 |