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Dependence of Work on the Pulling Speed in Mechanical Ligand Unbinding

[Image: see text] In single-molecule force spectroscopy, the rupture force F(max) required for mechanical unfolding of a biomolecule or for pulling a ligand out of a binding site depends on the pulling speed V and, in the linear Bell–Evans regime, F(max) ∼ ln(V). Recently, it has been found that non...

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Detalles Bibliográficos
Autores principales: Pham, Hong An, Truong, Duc Toan, Li, Mai Suan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389893/
https://www.ncbi.nlm.nih.gov/pubmed/34292743
http://dx.doi.org/10.1021/acs.jpcb.1c01818