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Predicting the Membrane Permeability of Fentanyl and Its Analogues by Molecular Dynamics Simulations
[Image: see text] The lipid membrane is considered a crucial component of opioid general anesthesia. The main drug used for the induction and maintenance of opioid anesthesia is fentanyl and its various analogues. However, these drugs have different clinical effects, and detailed atomic-level insigh...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389899/ https://www.ncbi.nlm.nih.gov/pubmed/34286980 http://dx.doi.org/10.1021/acs.jpcb.1c05438 |