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Nanomechanical Stability of Aβ Tetramers and Fibril-like Structures: Molecular Dynamics Simulations

[Image: see text] Alzheimer’s disease (AD) is a neurodegenerative disorder and one of the main causes of dementia. The disease is associated with amyloid beta (Aβ) peptide aggregation forming initial clusters and then fibril structure and plaques. Other neurodegenerative diseases such as type 2 diab...

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Detalles Bibliográficos
Autores principales: Poma, Adolfo B., Thu, Tran Thi Minh, Tri, Lam Tang Minh, Nguyen, Hoang Linh, Li, Mai Suan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389904/
https://www.ncbi.nlm.nih.gov/pubmed/34253022
http://dx.doi.org/10.1021/acs.jpcb.1c02322