Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents

[Image: see text] The potential anticancer effect of fluoroquinolone antibiotics has been recently unveiled and related to their ability to interfere with DNA topoisomerase II. We herein envisioned the design and synthesis of novel Ciprofloxacin and Norfloxacin nitric oxide (NO) photo-donor hybrids...

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Detalles Bibliográficos
Autores principales: Fallica, Antonino Nicolò, Barbaraci, Carla, Amata, Emanuele, Pasquinucci, Lorella, Turnaturi, Rita, Dichiara, Maria, Intagliata, Sebastiano, Gariboldi, Marzia Bruna, Marras, Emanuela, Orlandi, Viviana Teresa, Ferroni, Claudia, Martini, Cecilia, Rescifina, Antonio, Gentile, Davide, Varchi, Greta, Marrazzo, Agostino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389907/
https://www.ncbi.nlm.nih.gov/pubmed/34319100
http://dx.doi.org/10.1021/acs.jmedchem.1c00917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8389907/
https://www.ncbi.nlm.nih.gov/pubmed/34319100
http://dx.doi.org/10.1021/acs.jmedchem.1c00917

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