NucHMM: a method for quantitative modeling of nucleosome organization identifying functional nucleosome states distinctly associated with splicing potentiality

We develop a novel computational method, NucHMM, to identify functional nucleosome states associated with cell type-specific combinatorial histone marks and nucleosome organization features such as phasing, spacing and positioning. We test it on publicly available MNase-seq and ChIP-seq data in MCF7...

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Detalles Bibliográficos
Autores principales: Fang, Kun, Li, Tianbao, Huang, Yufei, Jin, Victor X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390234/
https://www.ncbi.nlm.nih.gov/pubmed/34446075
http://dx.doi.org/10.1186/s13059-021-02465-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8390234/
https://www.ncbi.nlm.nih.gov/pubmed/34446075
http://dx.doi.org/10.1186/s13059-021-02465-1

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